26
339
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6836 |
FIIN-2
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FIIN2 是一种 FGFR 的不可逆抑制剂,能够抑制 FGFR1 (IC50:3.1 nM),FGFR2 (IC50:4.3 nM),FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。 | |||
T39992 |
FGFR1 inhibitor-2
FGFR1 inhibitor-2 |
||
FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer. | |||
T61304 |
FGFR2-IN-1
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR2-IN-1是一种 FGFR 抑制剂,对 FGFR1、FGFR2和FGFR3具有抑制作用, IC50 分别为460、140和2200 nM。FGFR2-IN-1 可用于研究与 FGFR2 相关的癌症。 | |||
T60185 |
FGFR2-IN-3
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR2-IN-3 是一种具有口服活性的选择性 FGFR2抑制剂。 | |||
T62653 |
FGFR-IN-2
|
||
FGFR-IN-2 (compound 1) 是一种有效的 FGFR 抑制剂,能够作用于 FGFR1 (IC50: 7.3 nM)、FGFR2 (IC50: 4.3 nM)、FGFR3 (IC50: 7.6 nM) 和 FGFR4 (IC50: 11 nM)。FGFR-IN-2 具有潜力进行癌症研究。 | |||
T11279 |
FGFR1/DDR2 inhibitor 1
|
Discoidin Domain Receptor (DDR); FGFR; Others | Angiogenesis; Others; Tyrosine Kinase/Adaptors |
FGFR1/DDR2 inhibitor 1 是一种具有口服活性的成纤维细胞生长因子受体 1 和盘状蛋白域受体 2 的抑制剂,能够抑制 FGFR1 (IC50:31.1 nM) 和 DDR2 (IC50:3.2 nM),具有抗肿瘤作用。 | |||
T8492 |
BO-264
|
Apoptosis; FGFR | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
BO-264 是一种有口服活性的转化酸性卷曲螺旋 3 抑制剂,可特异性阻断 FGFR3-TACC3融合蛋白的功能。它诱导纺锤体检查点依赖的有丝分裂阻滞,DNA 损伤和细胞凋亡,具有广谱抗肿瘤活性。 | |||
T2609 |
Masitinib
AB1010,马赛替尼 |
Apoptosis; FAK; c-Fms; FGFR; Bcr-Abl; PDGFR; Src; c-Kit; Hck | Angiogenesis; Apoptosis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
Masitinib (AB1010) 是生物口服可利用的选择性 c-Kit 抑制剂 (对于人重组c-Kit,IC50=200 nM),它还抑制PDGFRα/β(IC50s=540/800 nM),Lyn(对 LynB 的IC50=510 nM),Lck,较小程度上抑制FGFR3和FAK。它有抗增殖,促凋亡活性,且毒性低。 | |||
T61473 |
FGFR2-IN-2
|
||
FGFR2-IN-2是一种选择性 FGFR2抑制剂, 其 IC50值为 29 nM. | |||
T64215 | FGFR3-IN-2 | ||
FGFR3-IN-2 (compound 18b) 是一种有效的、选择性的 FGFR3 抑制剂,能够抑制 FGFR3 (IC50: 4.1 nM) 和 VEGFR2 (IC50: 570 nM)。FGFR3-IN-2 能够用于研究膀胱癌。 | |||
T63850 |
FGFR2-IN-3 hydrochloride
|
||
FGFR2-IN-3 hydrochloride 是一种选择性的、口服具有活力的 FGFR2 抑制剂。 | |||
T78845 |
FGFR1/VEGFR2-IN-1
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR1/VEGFR2-IN-1 (compound 2b) 为FGFR1/VEGFR2抑制剂,适用于癌症研究。 | |||
T1975 |
Infigratinib
BGJ-398,NVP-BGJ398 |
Apoptosis; FGFR | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
Infigratinib (NVP-BGJ398) 是一种 FGFR 家族抑制剂,抑制 FGFR1,FGFR2,FGFR3和 FGFR4的 IC50分别为 0.9 nM,1.4 nM,1 nM,60 nM。 | |||
T5473 |
ASP5878
ASP-5878 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂,具有口服活性,具有潜在的抗肿瘤作用。 | |||
T16781 |
Rogaratinib
BAY1163877 |
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Rogaratinib (BAY1163877) 选择性抑制成纤维细胞生长因子受体。 | |||
T1948 |
AZD4547
|
VEGFR; FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
AZD4547 是FGFR 家族抑制剂,能够作用于FGFR1 (IC50:0.2 nM),FGFR2 (IC50:2.5 nM),FGFR3 (IC50:1.8 nM) 和FGFR4 (IC50:165 nM)。 | |||
T3714 |
SUN11602
SUN 11602 |
ERK; FGFR | Angiogenesis; MAPK; Tyrosine Kinase/Adaptors |
SUN11602 是新型的碱性苯胺化合物,具有成纤维细胞生长因子特性。 | |||
T4425 |
JK-P3
|
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。 | |||
T2064 |
Semaxinib
司马沙尼,SU5416 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Semaxinib (SU5416) 是一种选择性的 VEGFR(Flk-1/KDR) 抑制剂,其 IC50=1.23 μM。 | |||
T3726 |
Erdafitinib
厄达替尼,JNJ-42756493 |
Apoptosis; FGFR | Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors |
Erdafitinib (JNJ-42756493) 是一种喹喔啉衍生物,是一种具有口服活性的FGFR 家族抑制剂,抑制FGFR1/2/3/4活性的IC50分别为1.2、 2.5、3.0和5.7 nM。 | |||
T79880 |
FGFR4-IN-16
|
FGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
FGFR4-IN-16 (CY-15-2)为FGFR-4选择性共价抑制剂,适用于癌症研究领域。 | |||
T10372 |
ARQ 069
|
Others | Others |
ARQ 069 (3.8-60 μM; for 2 hours) reduces the degree of phosphorylation of FGFR (predominantly FGFR2) in a concentration-dependent manner, without decreasing β-actin. ARQ 069 shows an affinity for FGFR2 of 5.2 μM. ARQ 069 inhibits FGFR phosphorylation in K | |||
T63967 |
Multi-kinase-IN-2
|
||
Multi-kinase-IN-2 是口服具有活力的血管激酶 (angiokinase) 抑制剂。Multi-kinase-IN-2 能够显著抑制血管激酶的活性,如 VEGFR-1/2/3、PDGFRα/β、FGFR-1、LYN 和 c-KIT 激酶。Multi-kinase-IN-2 能够明显减弱 AKT 和 ERK 蛋白的磷酸化,并可诱导细胞凋亡 (apoptosis),具有抗癌作用。 | |||
T71944 |
FGF/PDGF/VEGF RTK Inhibitor
|
||
FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of hmvecs (ec50 = 420 nm). | |||
T36292 |
NSC 12
|
||
NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans (HSPGs). NSC 12 also binds several other, but not all, FGF isoforms with Kd values ranging between 16 and 120 μM, preventing them from forming HSPG/FGF/FGFR ternary complexes. NSC 12 inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduc... | |||
T3512 |
S49076 HCl
S-49076 Hydrochloride |
FGFR; c-Met/HGFR; TAM Receptor | Angiogenesis; Tyrosine Kinase/Adaptors |
S49076 HCl (S-49076 Hydrochloride) 是 MET、AXL/MER 和 FGFR1/2/3 的有效抑制剂。S49076 HCl 在体外和体内有效阻断 MET、AXL 和 FGFR 的细胞磷酸化并抑制下游信号传导。在细胞模型中,S49076 HCl (S-49076 Hydrochloride) 抑制 MET 和 FGFR2 依赖性胃癌细胞的增殖,阻断 MET 驱动的肺癌细胞迁移,并抑制表达 FGFR1/2 和 AXL 的肝癌细胞的集落形成。在肿瘤异种移植模型中,建立了口服 S49076 HCl (S-49076 Hydrochloride) 后 MET 和 FGFR2 抑制的良好药代动力学/药效学关系,并与对肿瘤生长的影响密切相关。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03357 |
FGFR2 Protein, Mouse, Recombinant (hFc)
KGFR,AU043015,KGFRTr,Bek,Fgfr7,svs,fibroblast growt... |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.1 kDa and the accession number is AAA39377.1. | |||
TMPY-01011 |
FGFR1 Protein, Human, Recombinant (His)
KAL2,FLT2,FGFBR,HRTFDS,OGD,FLG,HBGFR,bFGF-... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-03389 |
FGFR2 Protein, Mouse, Recombinant (His)
svs,Fgfr-7,fibroblast growth factor receptor 2<... |
Mouse | HEK293 Cells |
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1. | |||
TMPY-06036 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
FGFR-1,FLG,CD331,HH2,FLT2,KAL... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7. | |||
TMPY-06034 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL2 |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4. | |||
TMPK-00847 |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
FGFR2 β (IIIb),KGFR,BEK,CD332,K-s... |
Mouse | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2. | |||
TMPK-00475 |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His)
K-sam,KSAM,KGFR,CD332,Keratinocyte growth factor re... |
Cynomolgus | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.2 kDa and the accession number is A0A2K5TL84-1. | |||
TMPK-00398 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor 2,CD332,... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPK-00400 |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Fibroblast growth factor receptor 2,KGFR,FGFR |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3. | |||
TMPK-00399 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Keratinocyte growth factor receptor,K-sam,BEK,FGFR<... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPK-00397 |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
K-sam,CD332,KGFR,Keratinocyte growth factor recepto... |
Human | HEK293 Cells |
FGFR2 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.2 kDa and the accession number is P21802-1. | |||
TMPJ-00388 |
FGFR2IIIc Protein, Human, Recombinant (hFc)
FGFR2,FGFR2 beta,FGF... |
Human | HEK293 Cells |
FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802. | |||
TMPJ-00390 |
FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2,FGFR2 beta,FGF... |
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3. | |||
TMPJ-00389 |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
FGFR2,FGFR2IIIc,FGFR... |
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 72-95 KDa and the accession number is P21802. | |||
TMPY-00972 |
FGFR2 Protein, Human, Recombinant (His & hFc)
K-SAM,TK14,BBDS,fibroblast growth factor receptor 2... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPJ-00391 |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGF R2b,KGFR,BFR-1,FGFR2 β,FG... |
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3. | |||
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. | |||
TMPK-00394 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,... |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the ... | |||
TMPK-00392 |
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
CD331,FGFR-1,FLT-2,BFGFR,N-sam, |
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession numb... | |||
TMPK-00381 |
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
CD334,FGFR-4,FGFR4,FGF R4,TKF,JTK2 |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1. | |||
TMPK-00379 |
FGFR4 Protein, Human, Recombinant (His & Avi)
CD334,FGFR4,TKF,FGF R4,FGFR-4,MGC2 |
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1. | |||
TMPK-01322 |
FGFR4 Protein, Rhesus macaque, Recombinant (His)
TKF,JTK2,FGF R4,CD334,FGFR-4,FGFR... |
Rhesus | HEK293 Cells |
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the accession number is XP_028705775.1. | |||
TMPK-00380 |
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4,TKF,FGFR4 β,FGF R4,FGFR4 be... |
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1. | |||
TMPK-00378 |
FGFR4 beta Protein, Human, Recombinant (His & Avi)
JTK2,CD334,FGFR4 β,FGF R4,TKF,FGFR |
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1. | |||
TMPY-00973 |
FGFR3 Protein, Mouse, Recombinant (His & hFc)
FR3,Fgfr-3,Flg-2,CD333,Mfr3,fibroblast gro... |
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q7TSI8. | |||
TMPY-05761 |
FGFR1 Protein, Human, Recombinant (His), Biotinylated
FLT-2,KAL2,FGFBR,HRTFDS,BFGFR,fib... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4. | |||
TMPY-04371 |
FGFR1 Protein, Human, Recombinant (His & GST)
HRTFDS,CEK,OGD,FLG,FLT2,FGFBR,bFGF-R-1,N-SAM,fibrob... |
Human | Baculovirus Insect Cells |
FGFR1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75 kDa and the accession number is H9FRD4. | |||
TMPY-05777 |
FGFR1 Protein, Human, Recombinant (hFc)
N-SAM,OGD,HH2,HBGFR,FLT2,CEK,FLG,FGFR<... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.15 kDa and the accession number is NP_001341297.1. | |||
TMPY-06035 |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,C... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.7 kDa and the accession number is P11362-7. | |||
TMPY-01208 |
FGFR3 Protein, Mouse, Recombinant (His)
fibroblast growth factor receptor 3,Mfr3,HBGFR,CD333,FR3,sam... |
Mouse | HEK293 Cells |
FGFR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37 kDa and the accession number is Q7TSI8. | |||
TMPY-06033 |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
HBGFR,BFGFR,bFGF-R-1,FLG,FGFR-1,fibroblast... |
Human | HEK293 Cells |
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56 kDa and the accession number is H9FRD4. | |||
TMPY-01781 |
FGFR1 Protein, Mouse, Recombinant (His)
Flt-2,FLG,fibroblast growth factor receptor 1,bFGF-... |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.9 kDa and the accession number is P16092-1. | |||
TMPY-01782 |
FGFR1 Protein, Mouse, Recombinant (hFc)
Hspy,fibroblast growth factor receptor 1,bFGF-R-1,AW2 |
Mouse | HEK293 Cells |
FGFR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P16092-1. | |||
TMPK-00390 |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3,JTK4,ACH,FGF R3,FGFR2 α(III... |
Human | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2. | |||
TMPK-00388 |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
HSFGFR3EX,FGF R3,ACH,CD333,FGFR2 ... |
Human | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2. | |||
TMPK-00389 |
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3,FGFR3 β (IIIb),CD333,FGF R3,CEK2... |
Human | HEK293 Cells |
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2. | |||
TMPK-00385 |
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3,EC 2.7.10,FGFR3 β (IIIc),CD... |
Human | HEK293 Cells |
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1. | |||
TMPK-00386 |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
ACH,CD333,EC 2.7.10,FGFR3 α (IIIc),FGF... |
Human | HEK293 Cells |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607. | |||
TMPK-00391 |
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
HSFGFR3EX,FGFR3,FGF R3,ACH,CD333,FGFR<... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p... | |||
TMPK-00384 |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
CD333,EC 2.7.10,JTK4,FGFR3 α (IIIc),FG... |
Human | HEK293 Cells |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607. | |||
TMPK-00686 |
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
CEK,CD333,HSFGFR3EX,FGFR3,FGF R3,FGFR<... |
Mouse | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9. | |||
TMPK-00387 |
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
HSFGFR3EX,FGF R3,EC 2.7.10,CD333,FGFR<... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell p... | |||
TMPY-00351 |
FGFR2 Protein, Human, Recombinant (beta IIIc, His)
fibroblast growth factor receptor 2,TK14,FGFR |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (beta IIIc, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is P21802-21. | |||
TMPK-00401 |
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. | |||
TMPK-00396 |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
BFR-1,FGF R2a,TK25,TK14,BEK,BBDS,JWS,F... |
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42.5 kDa and the accession number is P21802-1. | |||
TMPY-01228 |
FGFR2 Protein, Human, Recombinant (aa 1-377, His)
TK14,CEK3,BEK,BBDS,CD332,TK25,KGFR,BFR-1,f... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-377, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41 kDa and the accession number is P21802-1. | |||
TMPY-04273 |
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TK25,ECT1,JWS,fibroblast growth factor receptor |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3. | |||
TMPY-06321 |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated
ECT1,CEK3,JWS,TK14,K-SAM,CD332,TK25,KGFR,f... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha(IIIb), His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.88 kDa and the accession number is NP_075259.4. | |||
TMPY-04390 |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST)
CFD1,ECT1,K-SAM,BEK,KGFR,CD332,JWS,BFR-1,fibroblast... |
Human | Baculovirus Insect Cells |
FGFR2 Protein, Human, Recombinant (aa 400-821, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.7 kDa and the accession number is P21802-1. | |||
TMPJ-00715 |
FGF-19 Protein, Human, Recombinant (His)
FGF-19,Fibroblast growth factor 19,FGF19 |
Human | E. coli |
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 distinct subfamilies of high-affinity FGF receptors (FGFRs): FGFR-1, -2, -3, and -4, all with intrinsic tyrosine kinase activity. FGFRs can be important for regulation of glucose and lipid homeostasis. FGF19 has important roles as a hormone produced in the ileum in response to bile ... | |||
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